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Prescription Drug Abuse

Although most people take prescription medications responsibly, there has been an increase in the nonmedical use or, as National Institute on Drug Abuse (NIDA) refers to, abuse of prescription drugs in the United States.

  • In 2004, among persons aged 12 or older, 2.4 million initiated nonmedical use of prescription pain relievers within the past year
  • There were 615,000 new nonmedical users of OxyContin® in 2004
  • Three fourths (73.8%) of past year initiates of nonmedical pain reliever use had used another illicit drug prior to using pain relievers nonmedically
  • Nearly all (99.1%) past year initiates of nonmedical OxyContin® use had used another illicit drug prior to using OxyContin® nonmedically


What Are The Concerns?

A number of published reports indicate that prescription drug abuse is on the rise in the United States. According to the 2003 National Survey on Drug Use and Health, 6.3 million Americans aged 12 and older have used prescription medications for nonmedical purposes in the prior 30 days.

AN ESTIMATED:

  • 4.7 million used pain relievers
  • 1.8 million used tranquilizers
  • 1.2 million used stimulants
  • 0.3 million used sedatives

The number of new nonmedical users of pain relievers increased drastically-from 573,000 in 1990 to 2.5 million in 2000. Overall, men and women have roughly similar rates of nonmedical use of prescription drugs (an exception is found among 12-17-year-olds, with more females likely to abuse these drugs).

The Drug Abuse Warning Network (DAWN), which monitors drug mentions (medications and drugs of abuse) from emergency departments (EDs) across the Nation, recently reported that two of the most frequently mentioned prescription medications in drug abuse-related cases are benzodiazepines (e.g., Valium, Xanax, Klonopin, and Ativan) and opioid pain relievers (e.g., oxycodone, hydrocodone, morphine, methadone, and combinations that include these drugs). In 2002, benzodiazepines accounted for 100,784 ED visits categorized as drug abuse-related cases and opioid pain relievers accounted for more than 119,000. Between 1994 and 2002, ED reports of hydrocodone
and oxycodone overdoses increased by 170% and 450%, respectively. While ED visits attributed to drug addiction have been increasing, suicide-related visits have remained stable since 1995.

What Types of Prescription Medications are Commonly Abused?

Several classes of medications that are commonly abused include opioids, central nervous system (CNS) depressants, and stimulants. Certain over-the-counter (OTC) medicines can also be abused when not taken as directed. It is important to note that many prescription drugs or OTC medications can produce dangerous health effects when taken concurrently or taken with alcohol.

Opioids

Opioids are commonly prescribed to treat pain. Examples of prescription opioids include morphine (Kadian, Avinza), codeine, oxycodone (e.g., OxyContin, Percodan, Percocet), hydrocodone (Lortab, Lorcet, Vicodin), propoxyphene (Darvon), fentanyl (Duragesic), and hydromorphone (Dilaudid). Opioids work in the brain to diminish the perception of pain. Opioids also can produce a sense of euphoria by affecting pleasure centers in the brain. This is often intensified when opioids are taken by routes other than those prescribed. For example, OxyContin can be crushed and snorted, or injected intravenously-this can enhance the euphoric effects, while at the same time increasing the risk for serious medical consequences, such as overdose.

CNS Depressants

CNS depressants commonly are prescribed to treat anxiety and sleep disorders because of their ability to slow normal brain function. These medications include barbiturates, such as mephobarbital (Mebaral), pentobarbital sodium (Nembutal), butalbital (Fioricet), and benzodiazepines such as diazepam (Valium), chlordiazepoxide HCl (Librium), alprazolam (Xanax), triazolam (Halcion), and others.

Stimulants

Stimulants, including dextroamphetamine (Dexedrine and Adderall) and methylphenidate (Ritalin and Concerta), are used primarily to treat attention deficit hyperactivity disorder, attention deficit disorder, and narcolepsy. These stimulants increase the amount of certain chemicals in the brain and peripheral nervous system. This can lead to increased blood pressure and heart rate, and increased blood glucose.

Who is Most Vulnerable?

Trends in Prescription Medication Abuse

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